Güncel Gönderiler: FEF, Kimya Bölümü Koleksiyonu
Toplam kayıt 472, listelenen: 1-20
-
Pd nanocatalyst supported on chitosan-waste oil microspheres for efficient degradation of industrial pollutants in water
(Springer, 2025)Disposal of industrial pollutants is one of the most important working topics today. Pd-doped catalysts have high efficiency in the degradation of many organic pollutants. Within the scope of this study, waste engine oil ... -
Design, synthesis, and urease inhibition activities of some bis-coumarin-perimidine hybrid compounds
(Springer, 2025)A series of bis-coumarin-perimidine hybrids were designed and synthesized, and their structures were characterized by FT-IR, H-1 NMR, C-13 NMR, and elemental analyses spectral data. All newly synthesized compounds were ... -
Theoretical determination of the biological activities of some benzimidazole derivative compounds with potential as active pharmaceutical agents
(al-Farabi Kazakh State National University, 2024)The biological activities of twelve different benzimidazole derivative compounds synthesized and registered in the literature were theoretically calculated with Way2Drug PASS software. Seven different biological activities, ... -
Molecular docking, bioactivity, adme, toxicity risks, and quantum mechanical parameters of some 1,2dihydroquinoline derivatives were calculated theoretically for investigation of its use as a pharmaceutical active ingredient in the treatment of multiple sclerosis (MS)
(Medical University, 2024 Prosp)In this study, some 1,2-dihydroquinoline derivatives, which have not been synthesized before, were designed, and their usability in the treatment of multiple sclerosis (MS) was investigated. Firstly, a docking study was ... -
Clinical and biochemical efficacies of green and white tea extract mouthwashes in the management of plaque-induced gingivitis
(Wiley, 2024)Objective: In this clinical study, chlorhexidine gluconate (CHX) was chosen as the positive control group, and the clinical and biochemical efficacy of mouthwashes with green tea, white tea and essential oil (EO) as the ... -
Bridging HPLC-ESI-MS/MS analysis and in vitro biological activity assay through molecular docking and network pharmacology: The example of European nettle tree (Celtis australis L.)
(Wiley, 2024)Celtis australis L. (Family: Cannabaceae) is commonly used to treat many diseases like gastrointestinal problems, menstrual bleeding and amenorrhea. The present study was designed to investigate the chemical constituents, ... -
Metal catalyst-free β-amination of branched rac-C8N-type such as C7N carbasugars via intramolecular aza-michael addition: Biological evolution, DFT studies and ADME properties
(Elsevier, 2025)In this study, a new stereospecific strategy for the preparation of C8N aminocyclohexenols such as C7N, validamine analogs were developed from starting compound 4 via intramolecular aza-michael β-amination reaction between ... -
Synthesis of arylated tetrahydrobenzo[H]quinoline-3-carbonitrile derivatives as potential hits for treatment of diabetes
(Taylor & Francis Ltd., 2024)Aim: Quinoline scaffolds are serving as the core structure for numerous antifungal, analgesic, antipyretic, anti-inflammatory drugs as well as have also been investigated for their potential antidiabetic properties. Though ... -
ATM kinase phosphorylates Ser15 of p53 in a pH-dependent manner
(Trakya University, 2024)The phosphorylation of Ser15 in the transactivation domain (TAD) of the tumor suppressor protein 53 (p53) by ataxia-telangiectasia mutated (ATM) kinase is a crucial step in the tumor suppressor function of p53. An understanding ... -
Urease inhibition activity studies of novel azabenzimidazole-derived compounds
(Springer, 2024)AbstractA new series of azabenzimidazole compounds was synthesized and characterized with spectral methods such as IR, 1H NMR, 13C NMR and elemental analysis. The target compounds were screened for urease, and acetylcholinesterase ... -
Theoretical examination of the usability of some benzimidazole derivatives as active pharmaceutical ingredient in the treatment of multiple sclerosis
(Springer, 2024)AbstractIn this study, the usability of twelve different benzimidazole derivatives as active pharmaceutical ingredients in the treatment of multiple sclerosis was investigated. For each molecule, a docking study was carried ... -
Engineered reduction of S-adenosylmethionine alters lignin in sorghum
(BMC, 2024)Background Lignin is an aromatic polymer deposited in secondary cell walls of higher plants to provide strength, rigidity, and hydrophobicity to vascular tissues. Due to its interconnections with cell wall polysaccharides, ... -
Metal-organic frameworks (MOFs) as an anti-reflective coating for crystalline silicon solar cells
(Springer, 2024)Enhancing the performance of the solar cells is a very challenging task and to prevent surface reflections of solar rays is one of the ways. Metal-organic frameworks (MOFs) are novel inorganic-organic crystalline porous ... -
Novel phthalocyanines bearing fluoro-methylquinolin substituents: Synthesis, characterization, photophysical and photochemical properties
(Elsevier, 2024)The novel 4-((6-fluoro-2-methylquinolin-4-yl)oxy)phthalonitrile (3a), 3-((6-fluoro-2-methylquinolin-4-yl)oxy)phthalonitrile (3b), tetra 6-fluoro-2-methylquinolin-4-yl)oxy substituted zinc(II) phthalocyanines (4a and 4b) ... -
Synthesis and characterization of some new 2,3-disubstituted quinazolin-4(3h)-one compounds, investigation of urease, and ache inhibition properties, molecular, and docking study
(Springer, 2024)Objective: Novel 2,3-disubstituted 4-oxoquinazoline-3(4H) derivatives containing oxadiazole, thiazolidinone ring, the 4-oxoquinazoline-3(4H) Schiff bases, and carbothioamide structure were synthesized. All the synthesized ... -
Diversely functionalized benzopyran scaffolds as potential lead candidates for treating Alzheimer's disease and diabetes
(Elsevier, 2024)The current study deals with the preparation of polyfunctional benzopyran derivatives 1–25, synthesized by the condensation of 2,4-dihydroxy benzophenone, substituted aldehydes, and malononitrile. These compounds were ... -
Small steps to the big picture for health-promoting applications through the use of chickweed (stellaria media): in vitro, in silico, and pharmacological network approaches
(Wiley, 2024)Stellaria media L., also called chickweed, is widespread in all parts of the world. In the present study, we investigated the biological properties and chemical profiles of different extracts (ethyl acetate, ethanol, ... -
Fine-tuning the element dose in nanoparticle synthesis is the critical factor determining nanoparticle's impact on plant growth
(Elsevier, 2024)This study elucidates the impact of element dose during nanoparticle (NPs) synthesis on plant growth indices. Novel NPs containing two essential micro-nutrients, zinc (Zn) and manganese (Mn), were co-doped on cerium oxide ... -
Synthesis of novel quinazolinone-triheterocyclic hybrides as dual inhibition of urease and ache
(Springer, 2024)New triheteroyclic compounds containing quinazolinone, thiophene, andthiadiazole /thiazolidinone structureswere synthesized and characterized by FT-IR, 1H–NMR, and13C–NMRspectral data. The new compounds’ inhibitory activities ... -
An inhibition potential on some metabolic enzymes (urease and xanthine oxidase), essential oil contents and antioxidant effect of Sideritis lanata L.
(Springer, 2024)While people use the aerial parts of some Sideritis species as tea and sweetener, some species are used for medicinal purposes. In this study, anti-urease, anti-xanthine oxidase, and antioxidant activity of Sideritis lanata ...
