Kurum Yazarı "Şen, Bayram" TF, Cerrahi Tıp Bilimleri Bölümü Koleksiyonu İçin Listeleme
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Does apoptotic index predict the response to neoadjuvant chemotherapy in patients with breast carcinoma?
Askan, Gökçe; Okcu, Oğuzhan; Öztürk, Çiğdem; Öztürk, Seda Duman; Şen, Bayram; Bedir, Recep (Galenos Publishing, 2023)Objective: Neoadjuvant chemotherapy (NACT) plays a major role in the treatment of patients with locally advanced breast carcinoma. Although most patients have benefited from NACT, the rate of residual tumors is still high ... -
An easy and practical prognostic parameter: tumor-stroma ratio in Luminal, Her2, and triple-negative breast cancers
Öztürk, Çiğdem; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (Assoc Medica Brasileira, 2022)OBJECTIVE: The stroma surrounding the tumor cells is important in tumor progression and treatment resistance, besides the properties of tumor cells. Studies on the tumor stroma characteristics will contribute to the knowledge ... -
The effect of high serum lipid level on benign gallbladder diseases
Uyan, Mikail; Şen, Bayram; Arpa, Medeni; Okçu, Oğuzhan (Effect Publishing Agency ( EPA ), 2022)There is a positive correlation between serum lipid levels and benign gallbladder diseases. We wanted to evaluate whether there is a relationship between the preoperative lipid profiles results with the presence of ... -
Effect of tumor-infiltrating immune cells (mast cells, neutrophils and lymphocytes) on neoadjuvant chemotherapy response in breast carcinomas
Okcu, Oğuzhan; Öztürk, Çiğdem; Yalçın, Nazlıcan; Yalçın, Anıl Can; Şen, Bayram; Aydın, Esra; Öztürk, Ahmet Emin (Elsevier, 2024)Introduction: Despite screening, the incidence of breast cancer is increasing worldwide. Neoadjuvant chemotherapy (NAC) response is one of the most important parameters taken into consideration in surgery, optimal adjuvant ... -
GLUT-1 expression in breast cancer
Okcu, Oğuzhan; Şen, Bayram; Öztürk, Çiğdem; Güvendi, Gülname Fındık; Bedir, Recep (Federation of Turkish Pathology Societies, 2022)Objective: Numerous studies have been conducted to predict the prognosis of breast cancers. The effect of glucose transporter protein 1 (GLUT-1), the main carrier protein responsible for glucose transport, was investigated ... -
High tumor infiltrating lymphocytes are associated with overall survival and good prognostic parameters in endometrial endometrioid carcinoma patients
Öztürk, Çiğdem; Askan, Gökçe; Öztürk, Seda Duman; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (Federation Turkish Pathology Soc., 2023)Objective: The mortality incidence of endometrial carcinomas (ECs) has increased in recent years. Therefore, recent studies have focused on the cellular and microenvironmental properties of ECs. Tumor-infiltrating lymphocytes ... -
A new practical method of estimating tumoral microenvironment parameters of possible prognostic significance in patients with invasive breast carcinoma: Combined microenvironment score
Öztürk, Çiğdem; Okcu, Oğuzhan; Öztürk, Seda Duman; Askan, Gökçe; Şen, Bayram; Bedir, Recep (Elsevier, 2023)Background and objective: In recent years, the tumor microenvironment has become increasingly recognized as an influential factor in breast cancer development and growth. The parameters that form the microenvironment are ... -
Nucleolus assessment in invasive breast carcinoma, an objective parameter for histological grading
Öztürk, Seda Duman; Öztürk, Çiğdem; Okcu, Oğuzhan; Şen, Bayram; Bedir, Recep (TUBİTAK Scientific & Technical Research Council Turkey, 2022)Background/aim: The nucleolus has the potential to provide insight into how many types of cancer will progress. In this study, we examined the evaluation of the nucleolus with a microscope in widespread breast cancer tumors ... -
Predicting response to neoadjuvant therapy with glucose transporter-1 in breast cancer
Öztürk, Seda Duman; Öztürk, Çiğdem; Okcu, Oğuzhan; Askan, Gökçe; Şen, Bayram; Bedir, Recep (Assoc Medica Brasileira, 2023)OBJECTIVE: Glucose transporter-1 is a marker involved in energy transport in cancer cells. It has been shown to be a poor prognostic factor in many cancer types, including breast cancer. However, there is no satisfactory ... -
Prognositc significance of microcystic elongated and fragmanted (MELF) myometrial ınvasion pattern: A retrospective study
Okcu, Oğuzhan; Askan, Gökçe; Şen, Bayram; Öztürk, Çiğdem; Öztürk, Seda Duman; Güvendi, Gülname Fındık (2022)Objective: Endometrioid endometrial carcinomas (EEC) are the most commonly diagnosed malignancies of the female genital tract. Myometrial invasion depth is one of the most significant pathological prognostic parameters. ... -
The prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast carcinomas
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Ayazoğlu, Muhammet Safa; Güvendi, Gülname Fındık; Öztürk, Seda Duman; Askan, Gökçe; Bedir, Recep (Elsevier, 2023)Background and objective: The prognostic importance of lymphoid cells in the tumor microenvironment and their effect on treatment response have been demonstrated in many cancer types. However, there are limited studies on ... -
Response to letter to the editor
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Ayazoğlu, Safa; Güvendi, Gülname Fındık; Öztürk, Seda Duman; Askan, Gökçe; Bedir, Recep (Elsevier, 2023)We would like to thank Dr. Altındağ for his interest in our publication (Prognostic significance of non-lymphoid immune cells of the tumor microenvironment, including neutrophils, eosinophils, and mast cells in breast ... -
Total thiol can contribute to differentiating prostate cancer from BPH: Prostate Thiol Index as a new player
Arpa, Medeni; Şen, Bayram; Eren, Hüseyin; Uzun, Hakkı; Okcu, Oğuzhan; Erel, Özcan (Wiley, 2021)To assess the distinctiveness of serum native thiol (NT), total thiol (TT) and disulfide (SS) levels in PCa patients, we created a new parameter, prostate thiol index (PTI) [tPSA (TTxPVxAge) (-1/2)]. We determined the ... -
Tumor Budding is a reliable predictor for death and metastasis in invasive ductal breast cancer and correlates with other prognostic clinicopathological parameters
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Arpa, Medeni; Bedir, Recep (Elsevier, 2021)Background and objective: Breast cancers are the most common type of cancer and the most common cause of mortality in women worldwide. Different prognostic factors are the subject of research to differentiate the prognosis ... -
Tumor budding is an independent prognostic factor to predict overall survival in endometrial endometrioid carcinoma: A retrospective study
Okcu, Oğuzhan; Şen, Bayram; Askan, Gökçe; Öztürk, Çiğdem; Öztürk, Seda Duman; Bedir, Recep (Sage Publications, 2022)Objective. Tumor budding defined as a tumor cell nest away from the main tumor, has been found to be associated with prognostic parameters in many cancer types. We aimed to investigate the relationship between tumor budding ... -
Tumor-infiltrating lymphocytes (TILs)/volume and prognosis: The value of TILs for survival in HER2 and TN breast cancer patients treated with chemotherapy
Okcu, Oğuzhan; Öztürk, Seda Duman; Öztürk, Çiğdem; Şen, Bayram; Yasin, Ayşe İrem; Bedir, Recep (Elsevier, 2022)Background and objective: The use of the tumor microenvironment as a target in creating treatment modalities and as a biomarker in predicting treatment response has become increasingly important. Tumor-infiltrating ...