Kurum Yazarı "Arpa, Medeni" TF, Cerrahi Tıp Bilimleri Bölümü Koleksiyonu İçin Listeleme
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Dynamic thiol/disulphide balance in patients undergoing hypotensive anesthesia in elective septoplasties
Kazancıoğlu, Leyla; Batçık, Şule; Arpa, Medeni; Erdivanlı, Başar; Özergin Coşkun, Zerrin; Erdivanlı, Özlem Çelebi; Bahçeci, İlkay; Kazdal, Hızır; Erel, Özcan; Neşelioğlu, Salim (Wiley-Hindawi, 2021)Objective We aimed to investigate the effects of hypotensive anaesthesia on oxidative stress with serum thiol/disulphide balance in patients undergoing elective septoplasty procedures under general anaesthesia. Methods ... -
The effect of high serum lipid level on benign gallbladder diseases
Uyan, Mikail; Şen, Bayram; Arpa, Medeni; Okçu, Oğuzhan (Effect Publishing Agency ( EPA ), 2022)There is a positive correlation between serum lipid levels and benign gallbladder diseases. We wanted to evaluate whether there is a relationship between the preoperative lipid profiles results with the presence of ... -
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
Topçu, Atilla; Öztürk, Aykut; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Taylor & Francis Ltd., 2022)Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ... -
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
Özdemir, Ayşe; Topçu, Atilla; Mercantepe, Tolga; Arpa, Medeni; Karakaş, Sibel Mataracı; Özdemir, Ali Sezin; Tümkaya, Levent; Mercantepe, Filiz (Verduci Publisher, 2023)OBJECTIVE: Burns are a global medical and economic problem. In addition to high costs, the lengthy therapeutic process and the emotional trauma experienced by patients and their families indirectly worsen the socioeconomic ... -
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
Deniz, Esra; Topçu, Atilla; Öztürk, Aykut; Öztürk, Seda Duman; Arpa, Medeni; Atak, Mehtap (Elsevier, 2022)Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ... -
Evaluating serum elastin levels in striae gravidarum
Gürlek, Beril; Ural, Ülkü Mete; Tuğcugil, Sibel; Arpa, Medeni; Önal, Özgür (Walter de Gruyter Gmbh, 2020)Objective: Striae gravidarum (SG) is the most common dermatological defect in pregnancy leading to cosmetic anxiety with unknown etiopathogenesis. the aim of the study was to analyze the relation between serum elastin ... -
Evaluation of periostin, fibronectin and tenascin-C in patients chronic otitis media with cholesteatoma
Birinci, Mehmet; Terzi, Suat; Demir, Emine; Çeliker, Metin; Okcu, Oğuzhan; Arpa, Medeni; Çelebi, Özlem; Özergin, Zerrin; Dursun, Engin (Springer, 2022)Background: Although many studies have investigated the mechanisms of cholesteatoma formation, its pathogenesis remains unclear. The aim of this study was to evaluate the levels of periostin, fibronectin and tenascin-C, ... -
The impact of diurnal variation of PSA on timing of measurement in prostate biopsy
Uzun, Hakkı; Arpa, Medeni (Wiley, 2019)Background Prostate-specific antigen (PSA) synthesis is related to testosterone, which has a diurnal rhythm. PSA might have a diurnal variation and the timing of measurement could change the clinical practice for prostate ... -
Increased serum concentration of netrin-1 after intravitreal bevacizumab injection: is it a compensatory mechanism to counteract drug side effects?
Okutucu, Murat; Fındık, Hüseyin; Aslan, Mehmet Gökhan; Arpa, Medeni (BMC, 2021)Background To evaluate alterations in the serum concentrations of vascular endothelial growth factor (VEGF) and netrin-1 after intravitreal bevacizumab (BCZ) injection for the treatment of diabetic macular edema (DME). ... -
Is netrin-1 deficiency responsible for inflammation and systemic diseases related to pseudoexfoliation?
Okutucu, Murat; Fındık, Hüseyin; Aslan, Mehmet Gökhan; Arpa, Medeni (Lippincott Williams & Wilkins, 2020)Precis: Serum netrin-1 levels are significantly lower in patients with pseudoexfoliation syndrome (PES) and pseudoexfoliative glaucoma (PEG) compared with the control group. Purpose: To investigate serum netrin-1 levels ... -
Neovasküler yaşa bağlı makula dejenerasyonlu olgularda serum vasküler endotelyal büyüme faktörü ve netrin-1 düzeyinin değerlendirilmesi: olgu kontrol çalışması
Okutucu, Murat; Fındık, Hüseyin; Uzun, Feyzahan; Aslan, Mehmet Gökhan; Arpa, Medeni (Türkiye Klinikleri Yayınevi, 2022)Amaç: Bu çalışmanın amacı, neovasküler yaşa bağlı makula dejenerasyonu (n-YBMD) hastalarında serum vasküler endotelyal büyüme faktörü [vascular endothelial growth factor (VEGF)] ve netrin-1 düzeyini sağlıklı kontrol grubu ... -
PET-CT and MR imaging in the management of axillary nodes in early stage breast cancer
Baran, Mehmet Tarık; Gündoğdu, Hasan; Demiral, Gökhan; Kupik, Osman; Arpa, Medeni; Pergel, Ahmet (Coll Physicians & Surgeons Pakistan, 2020)Objective: To discriminate between malignant or benign axillary lymph nodes in breast cancer using MRI, PET-CT, and sentinel lymph node biopsy. Study Design: Observational study. Place and Duration of Study: Department of ... -
The protective effects of trimetazidine against ovary ischemia-reperfusion injury via the TLR4/Nf-kB signal pathway
Öztürk, Aykut; Topçu, Atilla; Deniz, Esra; Öztürk, Seda Duman; Arpa, Medeni; Yılmaz, Eda Kutlu (Wiley, 2022)Late diagnosis and treatment of ovarian ischemia can lead to worsening of ischemia, irreversible damage to ovarian functions and infertility. In this process, there is no approved medical treatment that can reduce the ... -
Radioprotective effect of endogenous melatonin secretion associated with the circadian rhythm in irradiated rats
Rakıcı, Sema Yılmaz; Tümkaya, Levent; Erdivanlı, Özlem Çelebi; Yazıcı, Ufuk; Dursun, Engin; Arpa, Medeni; Mercantepe, Tolga (Taylor & Francis Ltd, 2019)Purpose: We investigated the radioprotective effect of endogenous melatonin release at different times associated with the circadian rhythm on head and neck radiotherapy. Materials and methods: Two groups of animals were ... -
Serum 25-hydroxy vitamin D, vitamin B12, and folic acid levels in progressive and nonprogressive keratoconus
Aslan, Mehmet Gökhan; Fındık, Hüseyin; Okutucu, Murat; Aydın, Emre; Oruç, Yavuz; Arpa, Medeni; Uzun, Feyzahan (Lippincott Williams & Wilkins, 2021)Purpose: To evaluate the serum 25-hydroxy vitamin D, vitamin B12, and folic acid (FA) levels in progressive and nonprogressive patients with keratoconus (KCN). Methods: Fifty-five patients with KCN (28 progressive and 27 ... -
Total thiol can contribute to differentiating prostate cancer from BPH: Prostate Thiol Index as a new player
Arpa, Medeni; Şen, Bayram; Eren, Hüseyin; Uzun, Hakkı; Okcu, Oğuzhan; Erel, Özcan (Wiley, 2021)To assess the distinctiveness of serum native thiol (NT), total thiol (TT) and disulfide (SS) levels in PCa patients, we created a new parameter, prostate thiol index (PTI) [tPSA (TTxPVxAge) (-1/2)]. We determined the ... -
Tumor Budding is a reliable predictor for death and metastasis in invasive ductal breast cancer and correlates with other prognostic clinicopathological parameters
Okcu, Oğuzhan; Öztürk, Çiğdem; Şen, Bayram; Arpa, Medeni; Bedir, Recep (Elsevier, 2021)Background and objective: Breast cancers are the most common type of cancer and the most common cause of mortality in women worldwide. Different prognostic factors are the subject of research to differentiate the prognosis ...