Konu "Rat" için TF, Cerrahi Tıp Bilimleri Bölümü Koleksiyonu listeleme
Toplam kayıt 35, listelenen: 1-20
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Agomelatine on cisplatin-induced nephrotoxicity via oxidative stress and apoptosis
(Springer, 2023)Drug-induced nephrotoxicity is the greatest deterrent to the use of cisplatin, which is a frequently used chemotherapeutic with proven efectiveness in cancer therapy. Agomelatine, which is used in the treatment of sleep ... -
Anti-inflammatory and antioxidant effects of infliximab in a rat model of intestinal ischemia/reperfusion injury
(Sage Publishing, 2012)The aim of this study was to investigate the possible protective effects of infliximab on oxidative stress, cell proliferation and apoptosis in the rat intestinal mucosa after ischemia/reperfusion (I/R). A total of 30 male ... -
Can dexmedetomidine be effective in the protection of radiotherapy-induced brain damage in the rat?
(Springer, 2021)Approximately 7 million people are reported to be undergoing radiotherapy (RT) at any one time in the world. However, it is still not possible to prevent damage to secondary organs that are off-target. This study, therefore, ... -
Damage induced by paracetamol compared with N-acetylcysteine
(Lippincott Williams & Wilkins, 2014)Background: This study investigated the effect of thiamine pyrophosphate (TPP) on oxidative liver damage induced in rats with high-dose paracetamol. Methods: Rats for this experiment were divided into the following groups: ... -
Effect of hippophae rhamnoides extract on oxidative oropharyngeal mucosal damage induced in rats using methotrexate
(Korean Soc Otorhinolaryngol, 2017)Objectives. the objective of this study is to investigate and evaluate the effect of Hippophae rhamnoides extract (HRE) on oropharyngeal mucositis induced in rats with methotrexate (MTX) through biochemical, gene expression, ... -
Effect of infliximab on acute hepatic ischemia/reperfusion injury in rats
(E-Century Publishing Corp, 2015)This study aimed to investigate the hepatoprotective and antioxidant effects of infliximab (IFX) against liver ischemia/reperfusion (I/R) injury in rats. A total of 30 male Wistar albino rats were divided into three groups: ... -
The effect of rocuronium, sugammadex, and their combination on cardiac muscle and diaphragmatic skeletal muscle cells
(Springer Link, 2012)Purpose: Rocuronium has been associated with muscle weakness when administered in prolonged infusions. The effect of sugammadex and rocuronium together on muscle is unknown. In this study, we examined the effects of ... -
Effect of sugammadex on rocuronium induced changes in pancreatic mast cells
(Sage Publications Inc, 2015)Mast cells play a vital role in hypersensitivity reactions. Rocuronium is known to cause mast cell mobilization, hypersensitivity, and pancreatitis. the aim of this study was to investigate the effects of sugammadex on ... -
The effects of amiodarone in ovarian injury due to oxidative stress and inflammation caused by ischemia-reperfusion
(Taylor & Francis Ltd., 2022)Objective Ovarian ischemia constitutes 2-3% of all gynecological emergencies. New-generation therapeutic agents need to be discovered, in addition to invasive interventions capable of reducing the risk of potential ovarian ... -
The effects of dexmedetomidine on early acute kidney injury in severely burned rats
(Verduci Publisher, 2023)OBJECTIVE: Burns are a global medical and economic problem. In addition to high costs, the lengthy therapeutic process and the emotional trauma experienced by patients and their families indirectly worsen the socioeconomic ... -
Effects of gadodiamide and gadoteric acid on lung tissue: A comparative study
(Wiley, 2022)We set out to investigate the effects of gadodiamide and gadoteric acid, used for magnetic resonance imaging, on the lungs. In this study, 32 male Sprague Dawley rats were used. These were allocated into four groups; The ... -
Effects of gadolinium-based contrast agents on submandibular gland tissue in rats
(Springer, 2018)The aim of this prospective animal study is to investigate the influence of multiple administrations of macrocyclic ionic (gadoteric acid) and linear nonionic (gadodiamide) gadolinium-based contrast agents (GBCA) on ... -
Effects of infliximab against carbon tetrachloride-induced intestinal injury via lipid peroxidation and apoptosis
(Sage Publications Ltd, 2019)Carbon tetrachloride (CCL4) is often employed in the production of chlorofluorocarbons, petroleum refining, oil and rubber processing, and laboratory applications. Oral, subcutaneous, and inhalation exposure to CCL4 in ... -
The effects of mobile phone exposure on mast cells in rat dura mater
(Soc Chilena Anatomia, 2019)Mobile phone use has increased rapidly. the central nervous system has been shown to be adversely affected by its electromagnetic field (EMF) resulting in headache and sleep disturbances. How the cells make up the CNS and ... -
Effects of sugammadex on immunoreactivity of calcineurin in rat testes cells after neuromuscular block: A pilot study
(Springer, 2012)Reversal of neuromuscular blockage induced by steroidal neuromuscular blocking agents such as rocuronium can be achieved using normal dose of sugammadex, which has been shown to be very effective for such reversal. In this ... -
The effects of vitamin B12 on the TLR-4/NF-κB signaling pathway in ovarian ischemia-reperfusion injury-related inflammation
(Elsevier, 2022)Ovarian ischemia is a gynecological emergency case that occurs as a result of ovarian torsion. Oxidative stress and inflammation play central roles in the development of ischemia/reperfusion injuries. We investigated the ... -
Exogenous ATP administration prevents ischemia/reperfusion-induced oxidative stress and tissue injury by modulation of hypoxanthine metabolic pathway in rat ovary
(Univ Federal Santa Maria, 2014)In this study, xanthine oxidase (XO), malondialdehyde (MDA), myeloperoxidase (MPO) and glutathione (GSH) levels in the ovarian tissues of rats during the development of ischemia and postischemia-induced reperfusion were ... -
Hepatoprotective effect of punica granatum seed oil extract on paracetamol intoxication in rat via inhibory effect of CYP2E1
(2018)Punica granatum seed oil enriched by punikalagins has been shown to have a therapeutic effect against antidiabetic, anticancer, antiinflammatory and some organ toxicities. We aimed to reveal both protective and therapeutic ... -
Histological investigation of the effects of tenoxicam on pulmonary complications of pneumoperitoneum - Tenoxicam reduces lung injuries caused by pneumoperitoneum
(2011)Objectives. Pneumoperitoneum increases intra-abdominal pressure and generates oxidative stress, which mediates tissue injury. One of the causes of oxidative stress production is an inflammatory reaction. Taking this into ... -
Investigation of the effect of the efficiency of noise at different intensities on the DNA of the newborns
(Medknow Publications & Media Pvt Ltd, 2016)Hearing loss can occur in newborns exposed to high-level noise; noise exposure can cause more physiological stress and can lead to DNA damage. This study was designed to determine DNA damage in newborn rats exposed to sound ...