Güncel Gönderiler: TF, Temel Tıp Bilimleri Bölümü Koleksiyonu
Toplam kayıt 664, listelenen: 21-40
-
The hepatoprotective effects of camellia sinensis on cisplatin-induced acute liver injury
(MDPI, 2024)Acute liver injury is an increasing global health problem. It is a widespread side effect of cisplatin treatment in the clinic and can lead to liver failure if not treated promptly. Previous studies have revealed that green ... -
Evaluation of endoplasmic reticulum stress in an experimental intestinal ischemia–reperfusion model in rats: the role of ozone therapy and trimetazidine
(MDPI, 2024)Aim: The objective of the study was to assess the impact of ozone (O3) and trimetazidine on the intestines following ischemia–reperfusion (I/R) injury through the investigation of endoplasmic reticulum stress. Methods: ... -
Positive effects of white tea on breast cancer: N-methyl-N-nitrozourea intraductal induced breast carcinoma model
(Elsevier, 2024)An objective of this study was to investigate the chemopreventive and therapeutic effects of white tea (WT) on breast cancer. Fifty Sprague-Dawley rats were divided into five groups: control, MNU, taxol, low dose white tea ... -
Prevalence and molecular characterization of ESBL/pAmpC producing faecal Escherichia coli strains with widespread detection of CTX-M-15 isolated from healthy poultry flocks in Eastern Algeria
(Elsevier, 2024)The intensification of livestock farming has led to the widespread use of massive amounts of antibiotics worldwide. Poultry production, including white meat, eggs and the use of their manure as fertiliser, has been identified ... -
Kaempferol reduces pyroptosis in acute lung injury by decreasing ADAM10 activity through the NLRP3/GSDMD pathway
(Elsevier, 2024)Sepsis-associated acute lung injury (SA-ALI) is a significant problem in intensive care units worldwide, and no specific treatment is currently available. Therefore, it is crucial to identify new potential therapeutic ... -
The effectiveness of concentrated growth factor in facial nerve crush injury
(Elsevier, 2024)Aim: To evaluate the effect of concentrated growth factor (CGF) on regeneration of facial nerve after crush injury. Materials and Methods: Fourteen rats were randomized into two groups. The control group (CG) (n = 7) ... -
“My stoma and me run away from life with my concerns”: a qualitative study
(Gümüşhane Üniversitesi, 2023)The aim of the study is to determine the perceptions and lived experiences of persons with a stoma. The study group of this qualitative study consisted of 14 persons with a stoma (ileostomy and colostomy) determined with ... -
Pandemic process in children
(İnönü Üniversitesi Tıp Fakültesi, 2023)Aim: When compared to adults, it is seen that the COVID-19 disease in children has a milder course. However, considering that there are cases with severe course and even death, it is aimed to analyze the COVID-19 PCR ... -
Factors affecting mortality in COVID-19 patients treated with intravenous immunoglobulin
(İnönü Üniversitesi Tıp Fakültesi, 2023)Aim: Intravenous immunoglobulin (IVIG), used as an option in the treatment of severe Coronavirus disease 2019 (COVID-19), has been shown to have effects on the suppression of the hyperinflammatory state through immunomodulatory ... -
FOBTs with lower detection limits increase the colonoscopy rates
(Türk Klinik Biyokimya Derneği, 2023)Aim: Colon cancer, accounting for almost 10% of all cancers in both genders worldwide, is the fourth most common cause of cancer-related deaths. Approximately 95% of cases are originated from adenomas. In recent years, ... -
Cellular immunity in individuals classified by antibody, after covid-19 infection/vaccine
(Türk Klinik Biyokimya Derneği, 2023)Aim: Regarding coronavirus disease (COVID-19), despite antibody measurement alone providing insufficient data, studies evaluating immune responses to vaccination or disease have focused on humoral immunity. Uncoupled humoral ... -
Tumor-infiltrating lymphocytes may predict prognosis in breast cancer patients receiving neoadjuvant chemotherapy
(2023)Objective: Investigation of the histopathological features in core biopsies can predict the chemotherapy responses and thus provide information about the prognosis of breast cancer patients. Tumor-infiltrating lymphocytes ... -
Targeting ITGβ3 to overcome trastuzumab resistance through epithelial–mesenchymal transition regulation in HER2-positive breast cancer
(MDPI, 2024)HER2-positive breast cancer, representing 15–20% of all breast cancer cases, often develops resistance to the HER2-targeted therapy trastuzumab. Unfortunately, effective treatments for advanced HER2-positive breast cancer ... -
Colorimetric and fluorimetric sensing of trace amount of Hg2+in real samples by a new rhodamine B-based Schiff base probe: Smartphone, living cell applications and DFT calculation
(Elsevier, 2024)In this study, a Schiff base-based probe, named as 2-((methyl benzoate-4-yl)methyleneamino)-3 ',6 '-bis(diethylamino)spiro[isoindoline-1,9 '-xanthene]-3-one (2), was successfully synthesized and characterized by various ... -
PAI1 regulates cell morphology and migration markers in trastuzumab-resistant HER2-positive breast cancer cells
(Multidisciplinary Digital Publishing Institute (MDPI), 2024)HER2-positive breast cancer is a significant cause of mortality. Overcoming trastuzumab resistance requires a deeper understanding of its molecular mechanisms to develop effective therapies. This study investigates the ... -
Chitosan-coated scorpion venom ameliorates acute lung injury caused by klebsiella pneumoniae
(Springer, 2024)Nosocomial infections caused by antibiotic-resistant bacteria result in significant economic costs and human health issues, including acute lung injury. The purpose of this study was to investigate the scorpion venom in ... -
Synthetic and non-synthetic inhibition of ADAM10 and ADAM17 reduces inflammation and oxidative stress in LPS-induced acute kidney injury in male and female mice
(Elsevier, 2024)Acute kidney injury (AKI) is a severe medical condition that can lead to illness and death. A disintegrin and metalloprotease (ADAM) protein family is a potential treatment target for AKI due to its involvement in inflammation, ... -
Factors affecting mortality in COVID-19 patients treated with tocilizumab
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024)The aim of our study was to evaluate the risk factors associated with mortality in COVID-19 patients. During March 2020 to March 2022, 136 patients who were treated with tocilizumab in the service and intensive care unit ... -
The role of platelet to lymphocyte ratio (plr) in predicting early treatment response in diffuse large b cell lymphoma
(Springer, 2024)Background: Systemic inflammatory response in diffuse large B-cell lymphoma (DLBCL) is closely related to disease prognosis. Our aim is to determine the role of pretreatment platelet-to-lymphocyte ratio (PLR) in predicting ...
